What is NSE co-location

Neuron Specific Enolase (NSE)

Small cell carcinoma © Dr. Gerhard Weigl

Neuron-specific enolase (NSE) is a special metabolic enzyme (sugar metabolism), and it occurs mainly in cells of the central and peripheral nervous system as well as in so-called neuroendocrine cells. These neuroendocrine cells are found in numerous organs and tissues:

  • Lung,
  • Gastrointestinal tract,
  • Thyroid,
  • Urogenital tract and much more

In medicine, the measurement of the NSE in the blood is used as a so-called “tumor marker”, especially for malignant tumors of the neuroendocrine system (“neuroendocrine carcinomas”). It means that after a diagnosis of neuroendocrine carcinomaE.g. in the lungs the NSE is determined in the blood. The level of the measured values ​​is used for assessment

  • the previous course of the disease,
  • the prognosis (assessment of the further course of the disease) and
  • the success of the therapy.

NoteThe measurement of the NSE or other tumor markers in the blood should not be used as a screening test for a tumor disease, because this laboratory value can also be increased in a number of benign diseases.